The term “runner’s knee” is a loose term used to describe pain around the knee. There are two common conditions associated with runner’s knee; Patellofemoral Pain Syndrome (PFPS) and Iliotibial Band Friction Syndrome (ITBS). There are many different causes of runner’s knee. Pain often comes on gradually with no specific mechanism of injury and is generally felt during or after a run, especially when going up or down stairs or after getting up from a prolonged seated position. Since there are so many different causes of runner’s knee, there is a multi-faceted approach to treatment.